PathoDetect Kit

In news– Pune-based Mylab Discovery Solutions private limited has launched PathoDetect Kit for TB detection recently.

What PathoDetect Kit?

It simultaneously detects multiple drug resistance to Rifampicin and Isoniazid in a single test(tuberculosis and multidrug-resistant tuberculosis).
Mylab had received Central Drugs Standard Control Organisation CDSCO, TB Expert Committee and ICMR approval for the first indigenous TB Detection kit to detect tuberculosis.
The kit has been named PathoDetect MTB RIF and INH drug resistance kit.
The kit is an RT-PCR-based kit for accurate detection and will be used with Mylab Compact device systems – which will allow automated testing of multiple samples within two hours.
The entire project was estimated at a cost Rs 275-300 crore and the test kit will cost Rs 650. This PathoDetect kit combined with the Mylab Compact device platform will fill the current gaps in tuberculosis testing,
With automation, the complete testing process can be done even in rural areas with the mobile molecular lab.
The test kits have been designed to work in ambient temperatures compared to existing PCR options which needed 2-8 degrees cold storage.
The TBConnect App — an Integrated TB Workflow app from diagnostics to treatment — will also directly push results to the central grid and needs no manual upload.
Presently there are two different tests to be conducted: one to detect TB and the other to check drug resistance – against only one drug (Rifampicin). With this kit, there will be no liquid handling and it is a cartridge-based system.

Note:

Annually, 20 lakh new cases of TB are detected and around 4.9 lakh deaths are reported every year due to the disease.
data indicates 25% of the global cases of TB were in India and there is a 5-18 per cent death rate in drug resistance.
Mylab and Serum Institute of India have come together to create a unique Cy-Tb solution which is Fast, Accurate, and Cost Effective.
The Drug Controller General of India has granted market authorisation to SII’s Cy-TB kit which can be used as skin test for diagnosis of latent tuberculosis.

Further reading: https://journalsofindia.com/world-tuberculosis-tb-day-2022/