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Home Science & Tech

Benefits of Indomethacin in Covid 19 care

December 22, 2020
in Science & Tech
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Benefits of Indomethacin in Covid 19 care
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Researchers point to the benefits of Indomethacin in Covid 19 care

What is Indomethacin?

  • It’s a drug that reduces pain, fever, swelling, and redness. 
  • It is also being used to reduce tumor-induced suppression of the immune system and to increase the effectiveness of anticancer drugs. 
  • It is a type of nonsteroidal anti-inflammatory drug
  • It is conventionally used in the treatment of rheumatoid arthritis, for faster symptomatic relief and preventing progression of pneumonia in COVID-19 patients.

About the study 

The study was done in two groups.

  •  One, involving 82 mild and moderate patients, used the Propensity Score Match technique to compare indomethacin and paracetamol-based treatments.
  • And in the second group, severe patients (22) were treated with indomethacin in addition to remdesivir.

What does the study say?

  • The researchers have found that patients treated with indomethacin had a reduction in the number of days to become fever-free, and reduction in cough and muscle pain by half compared to the paracetamol set. 
  • Only one patient of 82 in the indomethacin arm of the first group required supplementary oxygen, while 28 of 109 patients on paracetamol required supplementary oxygen.
  • It further says that no one in the second group deteriorated enough to require mechanical ventilation. 
  • There was no evidence of adverse reaction to indomethacin or deterioration of renal or liver function, they recorded.
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Source: The Hindu
Tags: Prelims

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